• Professor and Chair, Biomedical Engineering

Yin

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• M.D. at University of California, San Diego
• Ph.D. in Bioengineering at University of California, San Diego
• M.S. in Aeronautical Engineering at Massachusetts Institute of Technology
• B.S. in Aeronautical Engineering at Massachusetts Institute of Technology

News Stories & Tip Sheets:

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Using the chemical library Biomedical engineer finds sites that bind April 7, 2005 -- Combinatorial chemistry provides researchers a vast library from which to choose. A researcher studying drug design for nerve damage therapies has gotten her answer to questions by following some old advice: she used the library. It's not the kind of library her mother or teacher suggested, but a combinatorial chemistry library of many different protein sequences that some day might help her and her colleagues develop a successful timed drug delivery system.

Lessening the jolt Love taps preferred over jolt in heart defibrillation Sept. 22, 2004 -- A biomedical engineer at WUSTL has determined love taps are better than love jolts in addressing defibrillation. When it comes to affairs of the heart, love taps are preferred over love jolts. That is the result of a team of heart researchers including Igor Efimov, Ph.D., associate professor of biomedical engineering at Washington University in St. Louis, trying to effect a better implantable heart defibrillator. Efimov and his colleagues have modeled a system where an implantable heart defibrillator focuses in on rogue electrical waves created during heart arrhythmia and busts up the disturbance, dissipating it and preventing cardiac arrest.

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Yin was born in Kumming, China, and came over to the United States with his parents in 1948. He received all of his schooling in the United States. His clinical expertise is in cardiology, specifically in cardiac catheterization. His research interests span the spectrum from hemodynamics ,— the study of forces involved in blood flow — to soft tissue biomechanics to cell mechanics.

Today, in addition to crafting an outstanding biomedical engineering department, Yin's research focus is on the study of how cells respond to mechanical stimuli, either from the forces of fluid or stretching. Yin became famous when he demonstrated how a bladder infection could lead to a kidney infection through classic fluid dynamics. He also has made pioneering contributions to delineating the mechanical properties of various heart tissues and the changes brought about by human aging and hypertension.

Yin came to Washington University in 1997, from Johns Hopkins University School of Medicine and Johns Hopkins Hospital, where, since 1978, he had served in the medicine, physiology and biomedical engineering departments of the university. In 1988, he became professor of medicine and in 1989 professor of biomedical engineering. Since 1978, he had also served as staff physician in the Adult Cardiac Catheterization Laboratory of Johns Hopkins Hospital.