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Washington University in St. Louis News & Information > Faculty Experts at Washington University in St. Louis >
Marvin A. Brennecke Professor of Molecular Microbiology
Expertise: Molecular genetics of protozoan parasites; genomics, virulence and drug resistance; leishmania, leishmaniasis
Bio: Beverley is an international leader in the development of genetic and molecular tools for studying human parasites. He has put those innovations to use in extensive studies of Leismania major, a parasite that infects approximately 12 million people worldwide, causing significant death and disfigurement.
Education:
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Ph.D. in Biochemistry at University of California-Berkeley
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Undressing a deadly parasite
Protein "tuning" system lets scientists uncloak dangerous parasite
May 7,
2009 -- Researchers at the School of Medicine have found a way to dress and undress Leishmania, a parasite that causes death and disfigurement in developing countries. Scientists showed that they could control the parasite's ability to put on its carbohydrate coat, causing it to put on the whole coat, a lighter version or to forego the coat entirely.
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Scientists seek genes of deadly parasite
Deadly parasite's rare sexual dalliances may help scientists neutralize it
April 9,
2009 -- For years, microbiologist Stephen Beverley has tried to get the disease-causing parasite Leishmania in the mood for love. In this week's Science, he and colleagues at the National Institutes of Health report that they may have finally found the answer: Cram enough Leishmania into the gut of an insect known as the sand fly, and the parasite will have sex.
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Immune cell first responders
Scans show immune cells intercepting parasites
Dec. 10,
2008 -- Researchers may have identified one of the body's earliest responses to a group of parasites that causes illness in developing nations. In a paper published online in Public Library of Science Pathogens, scientists report that they tracked immune cells as they patrolled the second-shallowest layer of the skin in an animal model. Injections of a genetically modified form of the parasite Leishmania major caused the immune cells to turn from their patrols and move to intercept the parasites.
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