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Washington University in St. Louis News & Information > University Groups > School of Engineering & Applied Science >
Biomedical Engineering
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A tiny cage of gold responds to light, opening to empty its contents
An exquisite container
Nov. 3,
2009 -- A tiny cage of gold covered with a smart polymer responds to light, opening to empty its contents and resealing when the light is turned off. The smart nanocages could be used to deliver drugs directly to target sites, thus avoiding systemic side effects.
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Going platinum
New catalyst could boost cleaner fuel use
May 14,
2009 --
Material scientists at Washington University in St. Louis have developed a technique for a bimetallic fuel cell catalyst that is efficient, robust and two-to-five times more effective than commercial catalysts. The novel technique eventually will enable a cost effective fuel cell technology, which has been waiting in the wings for decades and should give a boost for cleaner use of fuels worldwide.
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Birds of a feather
Study finds particles, molecules prefer not to mix
May 4,
2009 --
In the world of small things, shape, order and orientation are surprisingly important, according to findings from a new study by chemists at Washington University in St. Louis. Lev Gelb, WUSTL associate professor of chemistry, his graduate student Brian Barnes, and postdoctoral researcher Daniel Siderius, used computer simulations to study a very simple model of molecules on surfaces, which looks a lot like the computer game "Tetris." They have found that the shapes in this model (and in the game) do a number of surprising things.
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Imaging device fits in the palm of a hand
Ultrasound imaging now possible with a smartphone
April 20,
2009 --
Computer engineers at Washington University in St. Louis are bringing the minimalist approach to medical care and computing by coupling USB-based ultrasound probe technology with a smartphone, enabling a compact, mobile computational platform and a medical imaging device that fits in the palm of a hand. William D. Richard, Ph.D., associate professor of computer science and engineering, and David Zar, research associate in computer science and engineering, have made commercial USB ultrasound probes compatible with Microsoft Windows mobile-based smartphones, thanks to a $100,000 grant Microsoft awarded the two in 2008.
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'Good as gold'
Novel technique changes lymph node biopsy, reduces radiation exposure in breast cancer patients
Jan. 13,
2009 --
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| David Kilper/WUSTL Photo |
| WUSTL biomedical engineers Younan Xia (left) and Lihong Wang examine the photoacoustic tomography machine (PAT) in Wang's Whitaker Building laboratory. |
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Information obtained from a new application of photoacoustic tomography (PAT) is worth its weight in gold to breast cancer patients. For the first time, Lihong Wang, Ph.D., Gene K. Beare Distinguished Professor in the Department of Biomedical Engineering, with a joint appointment in Radiology, and Younan Xia, Ph.D., James M. McKelvey Professor in Biomedical Engineering, with a joint appointment in chemistry in Arts & Sciences, both at Washington University in St. Louis, have used gold nanocages to map sentinel lymph nodes (SLN) in a rat noninvasively using PAT.
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'Chips off the old block'
Plant polymerases IV and V are special forms of Polymerase II
Jan. 6,
2009 -- It's a little like finding out that Superman is actually Clark Kent. A team of biologists at Washington University in St. Louis has discovered that two vital cellular components, nuclear RNA Polymerases IV and V (Pol IV and V), found only in plants, are actually specialized forms of RNA Polymerase II, an essential enzyme of all eukaryotic organisms, including humans.
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Chemist receives funding to unravel tricks of neuronal wiring
Midline crossing
Dec. 22,
2008 --
Joshua Maurer, Ph.D., assistant professor of chemistry in Arts & Sciences at Washington University in St. Louis, has received a four-year, $1,216,000 grant from the National Institute of Mental Health for research titled, "Unraveling Development: New Materials for Understanding Neuronal Wiring." Maurer's long term objective is to develop methodology that allows the study of a variety of neuronal wiring processes. He is starting by unscrambling a phenomenon known as midline crossing using zebrafish. During development, neurons from the right eye cross the midline of the brain to make a connection in the left hemisphere.
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Researchers solve piece of large-scale gene silencing mystery
Opening the "X-files" of biology
Dec. 4,
2008 --
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| Pikaard |
A team led by Craig Pikaard, Ph.D., WUSTL professor of biology in Arts & Sciences, has made a breakthrough in understanding the phenomenon of nucleolar dominance, the silencing of an entire parental set of ribosomal RNA genes in a hybrid plant or animal. Since the machinery involved in nucleolar dominance is some of the same machinery that can go haywire in diseases such as cancer, Pikaard and his collaborators' research may have important implications for applied medical research. Click here for a podcast from Genetic Engineering & Biotechnology News: Interview with Craig Pikaard.
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Partnership reaching students on a national level
Research-based undergraduate course expands beyond WUSTL
Nov. 25,
2008 --
Washington University in St. Louis is in the spotlight for its pivotal role in the Genomics Education Partnership, a collaborative effort to provide research experience in genomics to undergraduate classrooms across the country. At the helm of this mission is Sarah C.R. Elgin, Ph.D., WUSTL professor of biology and professor of education in Arts & Sciences, as well as professor of biochemistry & molecular biophysics and professor of genetics in the School of Medicine.
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Moving down the chain
Precise measurement of phenomenon advances solar cell understanding
Nov. 18,
2008 --
Researchers at Washington University in St. Louis have shed light on a basic process that could improve future solar cells. Dewey Holten, Ph.D., professor of chemistry in Arts & Sciences and graduate student Hee-eun Song have directly measured the rate of hole transfer between identical porphyrin compounds in their ground states. These results are key to understanding the fundamental processes underlying charge separation in this sort of structure and have applications for improving the efficiency of solar cells.
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