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Genetics

Biologists at Washington University are making advances in genetics in plants, mammals (including people), bacteria, algae and viruses. Applications include improved human health, a safer, cleaner agriculture, the engineering of benign organisms to deliver drugs, and a better understanding of plant and ecosystem history, to name a few. Chemists and biomedical engineers also make contributions to genetics studies. The Department of Computer Science has numerous researchers contributing to advances in bioinformatics and computational genomics, which increase the understanding of different organisms.
| Faculty Experts: |
Showing Genetics Experts 1 through 5 of 10.
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Tiffany Knight
 Assistant Professor of Biology

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| Knight |
Knight is an ecologist who studies the population ecology of rare and invasive plant species, and addresses questions related to the causes and consequences of their abundances and distributions. Why are some species rare, while their closely related congeners are widespread? How does dispersal ability ...

Expertise: Ecology, biology, plants, ecosystems, habitat

Direct contact: (314) 935-8282
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knight@wustl.edu

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James Cheverud
 Professor of Physical Anthropology in Arts and Sciences


Expertise: quantitative genetics, evolutionary theory, human genetics, human and nonhuman primate biology, genetics, obesity, evolution, …

Direct contact: (314) 362-4188
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cheverud@wustl.edu

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Ralph Quatrano

Ralph S. Quatrano, Ph.D., is the Spencer T. Olin Professor in Arts and Sciences and chair of the Department of Biology at Washington University in St. Louis. He is internationally known for his plant science work on patterns of embryo formation, and how the patterns lead cells to acquire traits or ...

Expertise: Plants, plant biology, botany, moss, genome, algae, genes, …

Direct contact: (314) 935-6850
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rsq@wustl.edu
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Glenn Davis Stone
 Professor of Sociocultural Anthropology and Environmental Studies in Arts & Sciences

Stone is an ecological anthropologist who has studied indigenous agricultural systems for the past 20 years. He has written extensively on intensification, labor organization, sexual division of labor, ethnicity and production, spatial organization and especially relationships between population, conflict ...

Expertise: ecological anthropology, political and historical ecology, agricultural biotechnology, settlement patterns, population, ethnoarchaeology, Web-based scholarship, …

Direct contact: (314) 935-5239
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stone@artsci.wustl.edu

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Ursula Goodenough
 Professor of Biology in Arts & Sciences

Leading cell biologist and Washington University professor of biology Ursula Goodenough, is the author of a bestselling textbook, Genetics, and also wrote the popular discourse on religion and science The Sacred Depths of Nature, which was named Oustanding Academic Book of 1999 by Choice. She has served ...

Expertise: evolution of sex, speciation

Media assistance: (314) 935-5272 / tony_fitzpatrick@wustl.edu

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Showing Genetics Experts 1 through 5 of 10.
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| News Stories & Tip Sheets: |
Showing Genetics Stories 1 through 3 of 79.
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'Nurture, sustain a culture of scientific innovation'
 Obama names WUSTL biologist to his science advisory council

May 7,
2009 --
President Obama has appointed Barbara A. Schaal, Ph.D., the Mary-Dell Chilton Distinguished Professor of biology in Arts & Sciences at Washington University in St. Louis and vice president of the National Academy of Sciences, to the President's Council of Advisors on Science and Technology.

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Discovery could lead to better rice yields
 Technology identified could reduce the spread of rice virus

Feb. 10,
2009 --
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| National Science Foundation |
Building on plant virus research started more than 20 years ago, a biologist at Washington University in St. Louis and his colleague at the Donald Danforth Plant Science Center in St. Louis have discovered a technology that reduces infection by the virus that causes Rice Tungro Disease, a serious limiting factor for rice production in Asia.

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'Chips off the old block'
 Plant polymerases IV and V are special forms of Polymerase II

Jan. 6,
2009 -- It's a little like finding out that Superman is actually Clark Kent. A team of biologists at Washington University in St. Louis has discovered that two vital cellular components, nuclear RNA Polymerases IV and V (Pol IV and V), found only in plants, are actually specialized forms of RNA Polymerase II, an essential enzyme of all eukaryotic organisms, including humans.

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Showing Genetics Stories 1 through 3 of 79.
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David Holtzman: Attacking Alzheimer's With a New Test for Amyloid Beta
U.S. News & World Report online

July 1,
2009 -- WUSTL neuroscientist David Holtzman and colleagues have devised a test that shows whether an experimental medication has a chance of working in Alzheimer's patients.

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Elaine Mardis and Richard Wilson: Taking Cancer's Genetic Measure
U.S. News & World Report online

July 1,
2009 -- WUSTL biochemists Elaine Mardis and Richard Wilson helped decode the human genome and are now working to find genetic mutations associated with acute myeloid leukemia.

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Study: 'Depression Gene' Doesn't Predict the Blues
Time.com

June 17,
2009 -- Are some people hardwired to get the blues? Scientists have long believed that a tendency toward melancholy runs in families. A new study published on June 16 in JAMA now threatens to send researchers back to the drawing board. The meta-analysis of 14 prior studies concludes that the so-called depression gene may not be associated with an elevated risk for depression, as many researchers had believed. WUSTL psychiatric geneticist Alexandre Todorov, whose 2007 peer-reviewed study was included in the JAMA piece, comments.

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Gene Mutation May Up Risks of Endometrial Cancer
U.S. News & World Report online
and 8 others

May 27,
2009 -- A genetic marker for aggressive endometrial cancer has been identified by U.S. researchers, who said their finding could lead to more targeted and risk-appropriate treatments. WUSTL gynecologic oncologist Israel Zighelboim comments on the study that appears online in the Journal of Clinical Oncology.

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Combo Screening Doesn't Spot Early Ovarian Cancer
U.S. News & World Report
and 3 others

March 24,
2009 -- A screening regimen that combines ultrasound and a blood test to detect a marker for ovarian cancer, fails to discover the cancer in its early stages and often results in unnecessary surgery, a new study shows. WUSTL ob gyn professor David Mutch, who wrote an accompanying journal editorial, comments.

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Control your DNA destiny
MSNBC.com

March 12,
2009 -- Some genetic traits are easier to defy than others. Others, such as cancer or diabetes, are not so simple to escape. Advice on how you can reduce your risk with proven tips for protecting your health from head to toe. WUSTL surgery professor Ming You, director of the Chemoprevention Program at WUSTL's Siteman Cancer Center, comments on the role heredity plays in asthma, allergies and lung cancer.

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Depression can break the heart
USA Today

March 4,
2009 -- Depression almost doubles the risk of developing heart disease over 12 years, according to a long-term study of twins. It contributes to the risk of heart disease as much as diabetes, high cholesterol or obesity does, says study leader and WUSTL psychiatry professor Jeffrey Scherrer.

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Push is on to tailor cancer care to tumor's genes
Associated Press
and 122 others

Feb. 17,
2009 -- The days of one-size-fits-all cancer treatment are numbered: A rush of new research is pointing the way to tailor chemotherapy and other care to what's written in your tumor's genes. WUSTL oncologist Matthew Ellis, co-inventor of a different breast cancer genetic approach, comments.

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Lowly worm offers new clues on stroke, heart drugs
Reuters
and 3 others

Jan. 30,
2009 -- Worms that can survive with almost no oxygen are teaching scientists how to rescue oxygen-starved cells in humans who suffer a heart attack or stroke, said WUSTL medical researcher Michael Crowder, whose study appears in Science.

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The Bush Legacy
The Boston Globe

Jan. 13,
2009 -- Examining the Bush legacy, which won't be an easy one for future historians to assess. While most unsuccessful presidencies involved presidents who were considered captives of events, unable to muster effective responses, Bush's was one of bold strokes that, for better or worse, will be debated for a long time. WUSTL law professor Rebecca Dresser, who serves on the President's Council on Bioethics, comments on the stem cell research decision.

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Black churches help enlist first-time blood donors
Reuters Health Medical News
and 4 others

Dec. 29,
2008 -- Black churches that hold blood drives after informing parishioners about the importance of blood donations for children with sickle cell disease will get a big upsurge in first-time donors, new research shows. WUSTL School of Medicine sickle cell researcher Michael DeBaun comments.

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Gene found to protect against lung cancer
United Press International
and 3 others

Dec. 5,
2008 -- British and U.S. medical scientists say they have identified a gene that protects the body from developing lung cancer. One of the lead researchers is WUSTL molecular cell biology professor Greg Longmore.

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New gene silencing pathway found in plants
ScientistLive.com (UK)

Nov. 18,
2008 -- WUSTL researchers led by WUSTL biology professor Craig Pikaard have made major headway in explaining a mechanism by which plant cells silence potentially harmful genes.

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Itching puzzles experts
The Miami Herald
and 18 others

Nov. 18,
2008 -- Scientists are baffled by one of humankind's most annoying problems — itching — an almost universal misery for which there is, as yet, no adequate explanation or treatment. The recent discovery of an ''itchy gene,'' however, may offer hope for better treatments, says WUSTL neuroscientist Zhou-Feng Chen.

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Alzheimer's Gene Slows Brain's Ability To Export Toxic Protein
ScienceDaily.com

Nov. 14,
2008 -- People who carry two copies of a particular gene have roughly eight to 10 times the risk of getting Alzheimer's disease than people who do not. WUSTL neuroscientist David Holtzman and graduate student Mary Beth Finn, were among the group of scientists that conducted research for this study.

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Experts Decode Cancer Patient's Genes, Seeking Treatment Clues
The New York Times
and 57 others

Nov. 6,
2008 -- For the first time, researchers have decoded all the genes of a person with cancer and found a set of mutations that might have caused the disease or aided its progression. Includes comments by Richard Wilson, senior study author and director of WUSTL's Genome Sequencing Center, and WUSTL hematologist Timothy Ley, director of the study.

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Gene Plays Key Role in Clubfoot
U.S. News & World Report
and 8 others

Oct. 28,
2008 -- The first gene linked to clubfoot has been identified by WUSTL researchers who analyzed the DNA of 35 extended family members of a male infant with clubfoot.

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Genetic Region Linked To Five Times Higher Lung Cancer Risk
ScienceDaily.com
and 11 others

Sept. 10,
2008 -- A narrow region on chromosome 15 contains genetic variations strongly associated with familial lung cancer, says a study conducted by scientists at Washington University School of Medicine in St. Louis and other institutions in the United States and the United Kingdom.

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FBI Paints Chilling Portrait of Anthrax-Attack Suspect
The Wall Street Journal

Aug. 7,
2008 -- In a series of court documents that were at turns chilling and bizarre, federal investigators said U.S. Army microbiologist Bruce Ivins misled government agents investigating the 2001 anthrax mailings, sent emails with language closely matching the handwritten letters sent to victims and had access to the strain of anthrax used in the crime. WUSTL microbial genetics expert George Weinstock, who was not involved in the investigation, comments.

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Neuron Killers
Science News

Aug. 4,
2008 -- The method by which "bad" proteins bump off neurons is also a matter of dispute. Scientists are drawing ever closer to solutions for these mysteries, and what they discover may one day help head off these diseases or even repair some damage after rogue proteins have vandalized the brain or spinal cord.

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Additional Information:
More News:
Epigenetics Study
Plants inherit traits from more than gene sequence
Feb. 22, 2002 -- Two plants, same species, same environment, same genetic sequence; yet one is a normal, healthy specimen of weedy mustard relative Arabidopsis thaliana, and the other is a tiny dwarf plant, shriveled, a mere shadow of its genetically identical neighbor.
Researcher traces gene development in 'last common link'
April 2002 - A researcher studying the last common link between invertebrate and vertebrate animals has found a key genetic change that separates the spineless from the backboned.
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