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Washington University in St. Louis News & Information > News Topics > Science & Technology >

Nanotechnology

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Showing Nanotechnology Stories 1 through 10 of 31.
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A tiny cage of gold responds to light, opening to empty its contents
 An exquisite container

Nov. 3,
2009 -- A tiny cage of gold covered with a smart polymer responds to light, opening to empty its contents and resealing when the light is turned off. The smart nanocages could be used to deliver drugs directly to target sites, thus avoiding systemic side effects.

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Europium discovery
 New element found to be a superconductor

May 18,
2009 --
Of the 92 naturally occurring elements, add another to the list of those that are superconductors. James S. Schilling, Ph.D., professor of physics in Arts & Sciences at Washington University in St. Louis, and Mathew Debessai, Ph.D., — Schilling's doctoral student at the time — discovered that europium becomes superconducting at 1.8 K (-456 °F) and 80 GPa (790,000 atmospheres) of pressure, making it the 53rd known elemental superconductor and the 23rd at high pressure.

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Going platinum
 New catalyst could boost cleaner fuel use

May 14,
2009 --
Material scientists at Washington University in St. Louis have developed a technique for a bimetallic fuel cell catalyst that is efficient, robust and two-to-five times more effective than commercial catalysts. The novel technique eventually will enable a cost effective fuel cell technology, which has been waiting in the wings for decades and should give a boost for cleaner use of fuels worldwide.

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High-tech miniature medicine
 Nanoparticles help detect disease and deliver drugs with pinpoint accuracy

April 21,
2009 -- Researchers at Washington University School of Medicine in St. Louis are studying military-like techniques to detect and destroy deadly pathogens, including cancerous tumors. Nanoparticles, invisible to the human eye, operate much like a laser-guided missile within the body. They are able to locate and even deliver medication directly to diseased areas with great accuracy in the laboratory. The researchers will soon begin testing the nanoparticles in human clinical trials.

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"Tiny" collaboration for health care
 Nanotechnology institute formed in St. Louis

March 25,
2009 -- Funding from the Missouri Life Sciences Research Fund, part of the 1998 state tobacco settlement, will establish the St. Louis Institute of Nanomedicine Working Group, a collaborative regional effort to apply advances in nanotechnology to the treatment of human diseases.

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Nanoscience pioneer explains new imaging techniques
 Alivisatos to speak on new technique for creating biological imaging tools

Feb. 23,
2009 -- Paul Alivisatos shares his pioneering work with nanocrystals to develop medical breakthroughs in biological imaging at the Assembly Series on Wednesday, March 4, at 11 a.m. in Graham Chapel.

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'Good as gold'
 Novel technique changes lymph node biopsy, reduces radiation exposure in breast cancer patients

Jan. 13,
2009 --
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| David Kilper/WUSTL Photo |
| WUSTL biomedical engineers Younan Xia (left) and Lihong Wang examine the photoacoustic tomography machine (PAT) in Wang's Whitaker Building laboratory. |
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Information obtained from a new application of photoacoustic tomography (PAT) is worth its weight in gold to breast cancer patients. For the first time, Lihong Wang, Ph.D., Gene K. Beare Distinguished Professor in the Department of Biomedical Engineering, with a joint appointment in Radiology, and Younan Xia, Ph.D., James M. McKelvey Professor in Biomedical Engineering, with a joint appointment in chemistry in Arts & Sciences, both at Washington University in St. Louis, have used gold nanocages to map sentinel lymph nodes (SLN) in a rat noninvasively using PAT.

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Tiny, roll-shaped disease fighters
 New disease-fighting nanoparticles look like miniature pastries

July 29,
2008 --
Ultra-miniature bialy-shaped particles — called nanobialys because they resemble tiny versions of the flat, onion-topped rolls popular in New York City — could soon be carrying medicinal compounds through patients' bloodstreams to tumors or atherosclerotic plaques. The nanobialys are an important addition to the stock of diagnostic and disease-fighting nanoparticles developed by researchers at the School of Medicine.

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An alternative to chemotherapy
 Nanoparticles tackle pediatric brain tumors

July 14,
2008 --
An interdisciplinary team of researchers at Washington University in St. Louis, led by Karen L. Wooley, Ph.D., James S. McDonnell Distinguished University Professor in Arts & Sciences, is a step closer to delivering cancer-killing drugs to pediatric brain tumors, similar to the tumor that Senator Ted Kennedy is suffering from. Such tumors are often difficult to completely remove surgically; frequently, cancerous cells remain following surgery and the tumor returns. Chemotherapy, while effective at treating tumors, often harms healthy cells as well, leading to severe side effects especially in young children that are still developing their brain functions. In an effort to solve this problem, the Wooley lab has developed polymeric nanoparticles that can entrap doxorubicin, a drug commonly used in chemotherapy, and slowly release the drug over an extended time period.

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Big things from small packages
 Nano-sized technology has super-sized effect on tumors

April 2,
2008 --
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| Nanoparticles (yellow) show that a treated tumor (left) has less blood vessel growth than an untreated tumor. |
Anyone facing chemotherapy would welcome an advance promising to dramatically reduce their dose of these often harsh drugs. Using nanotechnology, researchers at the School of Medicine have taken a step closer to that goal. The researchers focused a powerful drug directly on tumors in rabbits using drug-coated nanoparticles.

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